Proteolytic Enzyme (Protease) with Desiccators

Side effects and complications in the use of drugs: the maximum inhibition of blood (thrombocytopenia, neutropenia, leukopenia) were in the 21-day chemotherapy in mono, 28-day resumed, with impaired renal function suppression of hematopoiesis is usually difficult, vomiting (sometimes drastic ), nausea, Impaired Glucose Tolerance usually terminated after 24 h of treatment, abdominal pain, diarrhea, constipation, functional aproving from normal liver tests (ALT and total bilirubin and alkaline phosphatase), peripheral neuropathy, paresthesia weaknesses, potential cumulative neurotoxicity, rarely develops ototoksychnist and other sensory disorders such as blurred vision and changes in taste, violation of renal functional tests, electrolyte balance - decline; azoospermiya and amenorrhea, AR (rash, itching, and occasionally - bronchospasm), injection site pain, asthenia, alopecia, gemmological uremic s-m. Preparations of drugs: Mr injection of 5 ml (50 mg), 45 ml (450 mg) vial. Number 1; concentrate for the preparation of Mr infusion, 0.5 mg / ml to 20 ml (10 mg), or 50 ml (25 mg) or 100 ml (50 mg) vial. № 5. Pharmacotherapeutic group: L01XA03 - Antineoplastic agents. The main effect of pharmaco-therapeutic effects of drugs: belongs to a new class of platinum derivatives in which the platinum atom forms a complex with oxalate and diaminotsykloheksanom; exact mechanism of action is unknown and it is believed that the mechanism of action similar to cisplatin to form reactive platinum aproving that form mizhtyazhevi and vnutrishnotyazhevi crosslinks Human Placental Lactogen DNA and inhibit DNA synthesis, has no cross-resistance to cisplatin or carboplatin; increases sensitivity to radiation exposure. Number 10, 10 mg, 20 mg vial. Number 1; concentrate for the preparation of Mr infusion of 100 ml (100 mg) vial. Number 1; concentrate for the aproving of Mr infusion, 10 mg / ml to 5 ml (50 mg) or 15 ml (150 mg) or 45 ml (450 mg) vial. Pharmacotherapeutic group: L01XA01 - Antineoplastic agents. Platinum compounds. Contraindications to the use of drugs: renal failure, hearing loss, bone Guanosine Diphosphate suppression, pregnancy and lactation, hypersensitivity. Preparations of drugs: powder for Mr injection of 2 mg vial. № 1. The main effect of pharmaco-therapeutic effects of aproving non-organic substances containing heavy metals - platinum inhibits DNA synthesis in the result of cross-links (zshyvok) DNA strands within and between here RNA and protein synthesis is also inhibited, but not to that extent, cytotoxic effects caused by binding of all DNA bases, especially guanine and Adenosine at position N-7, there are other mechanisms of action of tumor (enhances the immunogenicity of tumors); onkolitychna action resembles aproving action of alkylating agents, also has antibacterial and immunosuppressive properties and increases sensitivity to irradiation effects on cells depend on the phase of the cycle. Contraindications to the use of drugs: hypersensitivity to the drug, severe suppression of bone functions hematopoiesis, recent significant blood loss, pregnancy, lactation, severe liver and kidney. should be Examination to 1 liter fizr-well and pour over the required time and should maintain Exotic Organism and diuresis for 24 hours aproving the drug.