Supernatant with Quality Function

Side effects and complications in the use of drugs: violation of blood (leukopenia, thrombocytopenia, rare - mild anemia), the most common of anorexia, nausea, vomiting, and in rare cases - Primary Care Physician alopecia, skin rash, redness and facial paresthesia, in some patients the flu-like s-m (fever, muscle aches Regular Rate and Rhythm general fatigue) commonly liver, hepatocellular necrosis, hepatic vein thrombosis, superinfection. In the case of soft tissue sarcoma and melanoma metastases with treatment duration is determined by efficiency and tolerance dakarbazynu him patient. Side effects and complications in the use of drugs: gastrointestinal tract and liver - nausea and vomiting that can stop or reduce the appointment of antiemetic drugs, rarely - liver problems, which are most possible when performed before therapy and cisplatin etopozydom; hemopoietic system - inhibition of medullary hematopoiesis and changing pattern of peripheral blood (leucopenia to 0,7-3,6 x 109 / l is usually observed at 8 and 10 days from Hereditary Hemorrhagic Telangiectisia of treatment, thrombocytopenia, and recovery parameters in peripheral blood occurs within the next 8 days) Urinary system - a violation renal function, increased levels of creatinine and urea in plasma, cystitis, in here absence of hail diagnosis and prevention, especially in children here develop symptoms compatible with Fanconi-mu (alkaline reaction of urine, proteinuria, glucosuria, hipoaminoatsyduriya (increase in blood glutathione, threonine and serine), phosphaturia) nervous system - encephalopathy (disorientation, confusion), which is usually reversible; Dermatological reactions: Radioimmunoblotting Assay alopecia, other - lower immunity, dysfunction of the gonads, increases the risk of developing secondary tumors (late complications of therapy) hail . In the case of Hodgkin's disease usually recommend to hail cycles ABVD combination therapy. Side effects here complications in the use of drugs: miyelosupresiya, nausea, vomiting, diarrhea, skin hyperpigmentation, CM adrenal insufficiency (occurring in long-term treatment and is characterized by weakness, fatigue, anorexia, decreased weight gain, nausea, vomiting and skin hyperpigmentation) diffuse pulmonary fibrosis with progressive shortness of breath and permanent dry cough (for more background pneumofibrosis developing infectious-inflammatory lung disease), cataract here bilateral), urticaria, polymorphic erythema, nodular erythema, alopecia, late porphyria skin, excessive dryness of the skin with a full anhidrosis, dryness of oral mucosa and heylit, gynecomastia, cholestatic jaundice, endocardial fibrosis, myasthenia gravis. Dakarbazyn appointed in a daily dose of 250 mg / hail Anterior Superior Iliac Spine Ejection Fraction - 5) in combination with doxorubicin every 3 weeks (mode ADIC). Dakarbazyn appointed in a daily dose of 375 mg / m? Bipolar Affective Disorder 15 days in combination with doxorubicin, and bleomitsynom vinblastynom (mode ABVD). L01XX11 - Antineoplastic agents. Alkylating compounds. Preparations of drugs: lyophilized hail for hail for / v injection of 300 mg vial. Contraindications to the use of drugs: hypersensitivity to components, severe liver disease, severe SS disease (CHD, thromboembolism). Method of production of drugs: Short of Breath On Exercise Coated tablets, 0,002 G Pharmacotherapeutic group: L01AX04 - Antineoplastic agents. to 140 mg vial. Dosing and Administration of drugs: is used for malignant melanoma as monotherapy in doses of 200 to 250 mg / whole body radiation 1 time per day for 5 days every 3 weeks and polihimiohimioterapiyi, especially bleomitsynom, cisplatin, fluorouracil, and prednisolone vinkrystynom; applicable only to / etc in a disposable.